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pentobarbital will lower the level or result of voriconazole by impacting hepatic enzyme CYP2C9/ten metabolism. Small/Significance Unfamiliar.pentobarbital will reduce the extent or influence of eplerenone by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Insignificant/Significance Unknown.
pentobarbital will lower the level or impact of fosaprepitant by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch.
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pentobarbital will reduce the level or effect of ondansetron by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Check. No dosage adjustment for ondansetron is recommended for clients on these drugs.
pentobarbital will lessen the extent or outcome of clarithromycin by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Small/Significance Not known.
Monitor Closely (2)pentobarbital will minimize the level or impact of buprenorphine, very long-performing injection by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Check Closely. People who transfer to buprenorphine extended-acting injection from transmucosal buprenorphine coadministered with CYP3A4 inducers really should be monitored to be certain buprenorphine plasma degrees are sufficient.
pentobarbital will decrease the level or check here effect of buspirone by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check.
pentobarbital decreases levels of vandetanib by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Avoid coadministration with potent CYP3A4 inducers; these drugs minimize publicity to vandetanib by around 40%.
Contraindicated (one)pentobarbital will lessen the extent or result of lumacaftor/ivacaftor by impacting hepatic/intestinal enzyme CYP3A4 metabolism.
pentobarbital will decrease the level or result of norgestrel by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Keep track of Intently. Moderate CYP3A4 inducers could minimize progestin focus; consider use of added barrier techniques
Pentobarbital is produced by the Danish company Lundbeck. Use of the drug for executions is illegal below Danish regulation, and when this was learned, soon after public outcry in Danish media, Lundbeck stopped marketing it to US states that impose the death penalty and prohibited US distributors to promote it to any buyers, such as state authorities, that follow or get involved in executions of humans.[17]
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pentobarbital will reduce the extent or outcome of ibuprofen by influencing hepatic enzyme CYP2C9/ten metabolism. Minor/Importance Mysterious.